Figure 16-36 shows how normal signaling works with a Ras protein acting downstream of an RTK.You examine a cell line with a constitutively active Ras protein that is always signaling.Which of the following conditions will turn off signaling in this cell line? Figure 16-36

Question

Figure 16-36 shows how normal signaling works with a Ras protein acting downstream of an RTK.You examine a cell line with a constitutively active Ras protein that is always signaling.Which of the following conditions will turn off signaling in this cell line?  Figure 16-36

Quizplus · Accepted Answer

Addition of a drug that blocks protein Y from interacting with its target will turn off signaling in the cell line with a constitutively active Ras protein. In normal signaling, protein Y activates Ras, leading to downstream signaling. By blocking the interaction between protein Y and its target, the pathway leading to Ras activation is disrupted, thereby turning off signaling. The other choices (A, B, and D) involve manipulating protein X or Y, but do not address the issue of the constantly active Ras protein, and therefore would not necessarily turn off signaling.

Figure 16-36 Shows How Normal Signaling Works with a Ras