Your friend is a pioneer in ES cell research.In her research, she uses an ES cell line that originated from an inbred strain of laboratory mice called FG426.She has just figured out methods that allow her to grow an entire liver from an ES cell and has successfully grown 10 livers.She demonstrates that the newly grown livers are functional by successfully transplanting one of the new livers into a FG426 laboratory mouse.
You are particularly excited about this, because you have a sick pet mouse called Squeaky.You are very attached to Squeaky, as you found him when you were out camping in New Hampshire.Unfortunately, Squeaky has developed liver disease and will not live much longer without a liver transplant.After you see your friend on TV talking about her new method for growing mouse livers, you immediately grab your cell phone to ask her whether Squeaky could have one of the newly grown livers.Just as you are about to dial your friend, you remember something you learned in cell biology and realize that instead, you should ask your friend about possibly creating mouse iPS cells for Squeaky's benefit.
A.Why do you think that one of the newly grown livers may not work in Squeaky?
B.Explain how the use of iPS cells could solve this problem.

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The Answer of Your friend is a pioneer in ES cell research.In her research, she uses an ES cell line that originated from an inbred strain of laboratory mice called FG426.She has just figured out methods that allow her to grow an entire liver from an ES cell and has successfully grown 10 livers.She demonstrates that the newly grown livers are functional by successfully transplanting one of the new livers into a FG426 laboratory mouse.
You are particularly excited about this, because you have a sick pet mouse called Squeaky.You are very attached to Squeaky, as you found him when you were out camping in New Hampshire.Unfortunately, Squeaky has developed liver disease and will not live much longer without a liver transplant.After you see your friend on TV talking about her new method for growing mouse livers, you immediately grab your cell phone to ask her whether Squeaky could have one of the newly grown livers.Just as you are about to dial your friend, you remember something you learned in cell biology and realize that instead, you should ask your friend about possibly creating mouse iPS cells for Squeaky's benefit.
A.Why do you think that one of the newly grown livers may not work in Squeaky?
B.Explain how the use of iPS cells could solve this problem.

Your Friend Is a Pioneer in ES Cell Research