A permanent alteration of the nucleotide sequence of the genome of an organism is called a(n)

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A permanent alteration of the nucleotide sequence of the genome is known as a mutation. A phenotype refers to the observable physical or biochemical characteristics of an organism. A karyotype refers to the number, size, and shape of chromosomes in an organism. Epigenetic changes refer to modifications in gene expression without altering the DNA sequence. Histones are proteins that help package DNA into chromosomes, but are not directly related to mutations.

A Permanent Alteration of the Nucleotide Sequence of the Genome