A client asks the nurse why he cannot take his monoamine oxidase inhibitor (MAOI) with diphenhydramine (Benadryl). Which response should the nurse provide?

Question

Quizplus · Accepted Answer

MAOIs inhibit the breakdown of monoamines, including norepinephrine, dopamine, and serotonin. When combined with diphenhydramine, there is a potential for the accumulation of these monoamines, causing hypertensive crisis, which is a life-threatening condition. Therefore, it is important to avoid the concomitant use of these medications.

A Client Asks the Nurse Why He Cannot Take His