Which statement describes the primary difference between centrally acting muscle relaxants and direct-acting antispasmodics?

Question

Quizplus · Accepted Answer

The primary difference between centrally acting muscle relaxants and direct-acting antispasmodics is their mechanism of action. Centrally acting agents, such as diazepam, baclofen, and tizanidine, work by inhibiting neurons of the central nervous system, particularly those in the brain and spinal cord, thereby reducing muscle tone and spasticity. In contrast, direct-acting antispasmodics, such as dantrolene, work at the level of the neuromuscular junction and skeletal muscles, by blocking the release of calcium ions and reducing muscle contraction. Therefore, the correct answer is C, which states that centrally acting agents inhibit neurons of the central nervous system, while direct-acting agents work at the level of the neuromuscular junction and skeletal muscles.

Which Statement Describes the Primary Difference Between Centrally Acting Muscle