A Nurse Is Teaching a Client the Importance of Taking

A nurse is teaching a client the importance of taking the medication as prescribed. Client teaching is guided by the nurse's knowledge of which principles of pharmacokinetics? Note: Credit will be given only if all correct choices and no incorrect choices are selected. Select all that apply.

A) A medication taken by injection must cross the membranes of the gastrointestinal tract to get to the bloodstream before it can be distributed throughout the body.
B) A drug may be exposed to several physiological processes while en route to target cells.
C) Liver enzymes may chemically change the drug.
D) Excretion organs such as kidneys and intestines must be healthy enough to eliminate the drug.
E) Many processes to which drugs are exposed are destructive, thereby helping facilitate the drug's movement throughout the body.