When you scratch a mosquito bite, you damage some cells. Damaged cells release histamine, which causes localized swelling. The swelling can crush cells, causing them to release more histamine. This is an example of:

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This is an example of positive feedback, as the initial scratching leads to the release of histamine, which causes more swelling and cell damage, leading to even more histamine release and swelling.

When You Scratch a Mosquito Bite, You Damage Some Cells