Horses and donkeys can mate successfully to produce mules, which are always sterile. Which genetic isolating mechanism prevents horses and donkeys from becoming a single species?

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Horses and donkeys can produce offspring, but the resulting mules are always sterile. This is an example of hybrid infertility, which prevents horses and donkeys from becoming a single species despite their ability to interbreed. Hybrid inviability refers to hybrids that do not develop to maturity or are not viable, while mechanical isolation, behavioral isolation, and temporal isolation are prezygotic isolating mechanisms that prevent mating or fertilization from occurring in the first place.

Horses and Donkeys Can Mate Successfully to Produce Mules, Which