Which of the following can affect a small, endangered population so severely that it goes extinct?

Question

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A small population may have lost alleles and/or has low genetic diversity, which can lead to inbreeding depression, reduced fitness, and even extinction. When individuals are closely related, they are more likely to inherit harmful mutations or alleles, which can accumulate over generations and reduce the population's adaptability and resilience to changing environmental conditions. Increased mating opportunities or artificial gene transfer may not be beneficial if the population is too small or lacks genetic diversity, as it can result in genetic swamping, outbreeding depression, or disruption of local adaptations. Sexual selection may also lead to a reduction in genetic diversity if selective pressures are too strong or biased, but it may not be as detrimental as lost alleles or low diversity in a small population.

Which of the Following Can Affect a Small, Endangered Population