Based on the Way Natural Selection Works, What Is the BEST

Based on the way natural selection works, what is the BEST way to make use of antibacterial soap?

A) Always use it because most bacteria will cause illness.
B) Always use it because it is unlikely that bacteria will evolve to become resistant to it.
C) Never use it because bacteria will evolve to become resistant to it.
D) Use it only when you need to be free of bacterial contamination, so bacteria will be less likely to evolve resistance to it.
E) Never use it because all bacteria are harmless.