Please Select the TRUE Statement Regarding Toll-Like Receptors (TLRs)

Please select the TRUE statement regarding Toll-like receptors (TLRs) .

A) A number of different TLRs have been described, all of which are found in the phospholipid membranes of endosomes and phagosomes.
B) TLRs anchored in the membrane of endosomes generally detect components of the outermost layers of microbial cells, including lipopolysaccharide (LPS) , lipoproteins, and flagellin.
C) TLRs allow cells to detect patterns associated with microbes, indicating that the innate immune responses involve some specificity (although not the specificity of adaptive immunity) .
D) TLRs represent a very important early-warning system for viral infections. They allow any virally infected cell to alert neighboring cells that a virus is present.
E) All of these statements are true of TLRs.