List the pathophysiologic processes involved in appendicitis in sequential order.
A)The appendix becomes distended with fluid secreted by its mucosa.
B)The proximal lumen of the appendix becomes obstructed.
C)Purulent exudate forms and causes further distention of the appendix.
D)Pressure within the lumen of the appendix increases.
E)Tissue necrosis occurs and gangrene develops.

Question

Quizplus · Accepted Answer

Obstruction of the proximal lumen of the appendix is apparent in most acutely inflamed appendices. Following obstruction, the appendix becomes distended with fluid secreted by its mucosa. Pressure within the lumen of the appendix increases, impairs its blood supply, and leads to inflammation, edema, ulceration, and infection. The purulent exudate formed causes further distention of the appendix. If treatment is not initiated, tissue necrosis and gangrene result within 24-36 hours, leading to perforation (rupture).

List the Pathophysiologic Processes Involved in Appendicitis in Sequential Order