Why is kidney damage often observed in clients with systemic lupus erythematosus (SLE)?
A)SLE involves unusually high levels of circulating antigens. Because the kidneys play a critical role in filtering these antigens from the blood, they are under excess stress in clients with SLE.
B)SLE is commonly treated with nonsteroidal anti-inflammatory drugs (NSAIDs). Because these medications carry a high risk of nephrotoxicity, their use often leads to kidney damage in clients with SLE.
C)SLE involves deposition of immune complexes in the body's connective tissues. Because connective tissue makes up a significant portion of the kidneys, these organs are a frequent site of damage in SLE.
D)SLE involves unusually high levels of circulating antibodies. Because the kidneys play a critical role in filtering these antibodies from the blood, they are under excess stress in clients with SLE.

Question

Quizplus · Accepted Answer

A)SLE involves deposition of antigen-antibody complexes, also known as immune complexes, in the body's connective tissues. Because connective tissues makes up a large portion of the kidneys, these organs are frequently damaged in SLE. Note that the kidneys do not filter either antigens or antibodies from the blood. Also, even though NSAIDs are commonly used in the treatment of SLE and may exert nephrotoxic effects, use of NSAIDs is not the primary reason why kidney damage is often observed in clients with SLE.
B)SLE involves deposition of antigen-antibody complexes, also known as immune complexes, in the body's connective tissues. Because connective tissues makes up a large portion of the kidneys, these organs are frequently damaged in SLE. Note that the kidneys do not filter either antigens or antibodies from the blood. Also, even though NSAIDs are commonly used in the treatment of SLE and may exert nephrotoxic effects, use of NSAIDs is not the primary reason why kidney damage is often observed in clients with SLE.
C)SLE involves deposition of antigen-antibody complexes, also known as immune complexes, in the body's connective tissues. Because connective tissues makes up a large portion of the kidneys, these organs are frequently damaged in SLE. Note that the kidneys do not filter either antigens or antibodies from the blood. Also, even though NSAIDs are commonly used in the treatment of SLE and may exert nephrotoxic effects, use of NSAIDs is not the primary reason why kidney damage is often observed in clients with SLE.
D)SLE involves deposition of antigen-antibody complexes, also known as immune complexes, in the body's connective tissues. Because connective tissues makes up a large portion of the kidneys, these organs are frequently damaged in SLE. Note that the kidneys do not filter either antigens or antibodies from the blood. Also, even though NSAIDs are commonly used in the treatment of SLE and may exert nephrotoxic effects, use of NSAIDs is not the primary reason why kidney damage is often observed in clients with SLE.

Why Is Kidney Damage Often Observed in Clients with Systemic