Rejection of a donor kidney that begins months to years after transplant surgery and does not respond to increased immunosuppression would be categorized as which type of rejection?
A)Acute rejection
B)Chronic rejection
C)Delayed rejection
D)Nonimmune rejection

Question

Quizplus · Accepted Answer

A)Acute rejection develops within months of the transplant. It is caused by a cellular immune response and may be managed with methylprednisolone and OKT3 monoclonal antibody. Chronic rejection, which may develop months to years following the transplant, is a major cause of graft loss. Both humoral and cellular immune responses are involved in chronic rejection. Chronic rejection does not respond to increased immunosuppression.
B)Acute rejection develops within months of the transplant. It is caused by a cellular immune response and may be managed with methylprednisolone and OKT3 monoclonal antibody. Chronic rejection, which may develop months to years following the transplant, is a major cause of graft loss. Both humoral and cellular immune responses are involved in chronic rejection. Chronic rejection does not respond to increased immunosuppression.
C)Acute rejection develops within months of the transplant. It is caused by a cellular immune response and may be managed with methylprednisolone and OKT3 monoclonal antibody. Chronic rejection, which may develop months to years following the transplant, is a major cause of graft loss. Both humoral and cellular immune responses are involved in chronic rejection. Chronic rejection does not respond to increased immunosuppression.
D)Acute rejection develops within months of the transplant. It is caused by a cellular immune response and may be managed with methylprednisolone and OKT3 monoclonal antibody. Chronic rejection, which may develop months to years following the transplant, is a major cause of graft loss. Both humoral and cellular immune responses are involved in chronic rejection. Chronic rejection does not respond to increased immunosuppression.

Rejection of a Donor Kidney That Begins Months to Years