Leber Congenital Amaurosis (LCA)is a Disorder Characterized by Early-Onset Retinal

Leber congenital amaurosis (LCA) is a disorder characterized by early-onset retinal dystrophy which causes severe visual impairment beginning in infancy.The most common cause of the disorder is a mutated intron located in gene CEP290.Targeted deletion of the mutated intron shows promise as a treatment for LCA.The treatment of LCA is an example of the application of which of the following types of biotechnology?

A) PCR
B) cloning
C) recombinant DNA technology
D) microarrays
E) genome editing