Researchers found that phenothiazines reduced psychotic symptoms but also caused Parkinsonian symptoms, like tremors. This discovery suggests that:

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Phenothiazines work by blocking dopamine receptors, which reduces psychotic symptoms in schizophrenia by counteracting excessive dopamine. However, because dopamine is also involved in controlling movement, blocking its action can lead to Parkinsonian symptoms, indicating a link between schizophrenia and excessive dopamine rather than Parkinson's disease itself.

Researchers Found That Phenothiazines Reduced Psychotic Symptoms but Also Caused