An 8-year-old healthy boy is concerned about his very short stature. His growth hormone level is within normal limits despite the fact that his growth rate and bone age are below the norm for children of the same chronologic age. The level of which of the following hormones is most likely to be abnormal?

Question

Quizplus · Accepted Answer

Insulin-like growth factor I (IGF-I) is a key hormone that mediates the effects of growth hormone (GH) on growth. If a child has normal GH levels but is experiencing reduced growth and delayed bone age, it suggests that the issue may lie in the action or production of IGF-I, rather than in the production of GH itself.

An 8-Year-Old Healthy Boy Is Concerned About His Very Short