A 56-year-old obese woman suffering from heartburn and regurgitation of acid saliva after large meals is treated with cimetidine. During cimetidine treatment, her serum creatinine concentration increases significantly. The increase in serum creatinine with cimetidine treatment is most likely due to:

Question

Quizplus · Accepted Answer

Cimetidine can increase serum creatinine levels by competing with creatinine for renal tubular secretion, leading to decreased renal excretion of creatinine without necessarily indicating a decline in renal function.

A 56-Year-Old Obese Woman Suffering from Heartburn and Regurgitation of Acid