A 69-year-old man is diagnosed with benign prostatic hypertrophy (BPH). Which of the following hormones is primarily responsible for prostatic enlargement in BPH?
A) Testosterone
B) Androstenedione
C) Dihydrotestosterone (DHT)
D) Estrone
E) Estradiol

Question

Quizplus · Accepted Answer

Dihydrotestosterone (DHT) is the primary hormone responsible for prostatic enlargement in benign prostatic hypertrophy (BPH). Testosterone is converted to DHT by the enzyme 5-alpha-reductase in prostate cells, and DHT has a more potent effect on prostate growth than testosterone.

A 69-Year-Old Man Is Diagnosed with Benign Prostatic Hypertrophy (BPH)