A 49-year-old woman with coronary artery disease is prescribed a calcium channel blocker to facilitate coronary vasodilatation. Because of their myocardial side-effects, drugs that block L-type calcium channels would be expected to do which of the following?

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ECalcium channel blockers facilitate coronary vasodilation and are used to lower blood pressure (C) by causing relaxation of the vascular smooth muscle. They also lengthen the plateau phase of the ventricular action potential (E) by slowing the influx of calcium, which is crucial for the action potential in cardiac muscle cells. This effect can lead to a decrease in heart rate and a reduction in the force of cardiac contractions, which is beneficial in conditions like hypertension and angina.

A 49-Year-Old Woman with Coronary Artery Disease Is Prescribed a Calcium