A 30-year-old man develops adult respiratory distress syndrome (ARDS) after near-drowning due to a boating accident. Conventional mechanical ventilation and inhaled nitric oxide (NO) do not provide sufficient oxygenation. The partial pressure of arterial carbon dioxide (PaCO2) and fraction of inspired oxygen (FIO2) ratio as well as shunt fraction (Qs/Qt) improve greatly after bronchial instillation of surfactant. The improvements in respiratory function occurred because surfactant decreased which of the following?
A) Bronchiolar smooth muscle tone
B) Arterial bicarbonate concentration
C) Lung compliance
D) The work of breathing
E) Functional residual capacity (FRC)
Correct Answer:
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