Al and Zack are twins with end-stage renal failure due to Alport syndrome. Both are on chronic dialysis and make no urine. Following dialysis, they both weigh the same and have identical serum osmolalities. On the way home from a dialysis session, they stop at Vino's for lunch. Al drinks 1 liter of pale ale and eats a pepperoni calzone (sodium content 140 mEq). Zack, the designated driver, isn't hungry but drinks 2 liters of lager. When (if) they arrive home, which of the following statements would be true?
A) Zack's total body water is less than Al's.
B) Zack's serum osmolality is greater than Al's.
C) Zack's intracellular fluid (ICF) volume is greater than Al's.
D) Zack's extracellular fluid (ECF) volume is greater than Al's.
E) Zack's plasma sodium level is greater than Al's.

Question

Quizplus · Accepted Answer

Zack's intracellular fluid (ICF) volume is greater than Al's because he consumed more fluid (2 liters of lager) compared to Al (1 liter of pale ale), leading to a greater distribution of water into the ICF.

Al and Zack Are Twins with End-Stage Renal Failure Due