Lambert-Eaton Syndrome (LES) is similar to myasthenia gravis. In LES, which of the following is most affected during neuromuscular transmission? A) The driving force for Ca²⁺ influx in the nerve terminal B) The synthesis of acetylcholine (ACh) in the nerve terminal C) The release of ACh from the nerve terminal D) The degradation of ACh in the synaptic cleft E) The response to ACh in the muscle membrane

Question

Quizplus · Accepted Answer

Lambert-Eaton Syndrome (LES) primarily affects the release of acetylcholine (ACh) from the nerve terminal, leading to muscle weakness. This is due to antibodies against presynaptic calcium channels, which are crucial for ACh release.

Lambert-Eaton Syndrome (LES) Is Similar to Myasthenia Gravis