In 2007,carbamazepine became the first mainstream medication to carry a recommendation by the Food and Drug Administration that patients of Asian descent be tested for the HLA-B*1502 gene before starting drug therapy.Asian patients are almost exclusively carriers of this gene,and if placed on carbamazepine,might develop Stevens-Johnson syndrome.What is the most significant outcome of this recommendation?

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This announcement heralded the start of an era that is sure to continue,that is,the ability to make decisions about which medications patients should or should not take based on their ethnicity and/or race.Stevens-Johnson syndrome is a severe side effect of many medications; therefore,this finding will not provide for early detection.Likewise,it will not provide a cure for the syndrome.Although this recommendation may guide genetically based nursing care,it is not the most significant outcome.

In 2007,carbamazepine Became the First Mainstream Medication to Carry a Recommendation