In the UK,Phenylketonuria (PKU)has an incidence of around 1 in 10,000 live births (NSPKU,2004),and it is estimated that how many people may be carriers of the recessive gene responsible for PKU?

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PKU is a recessive genetic disorder, so carriers have one copy of the gene. The carrier frequency can be estimated using the Hardy-Weinberg principle. If the incidence of PKU is 1 in 10,000, the carrier frequency is approximately 1 in 70.

In the UK,Phenylketonuria (PKU)has an Incidence of Around 1 in 10,000