Doubling the chromosomes of a sterile species hybrid with colchicine or cold shock is a method used to produce a fertile species hybrid (amphidiploid).

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Doubling the chromosomes of a sterile species hybrid with colchicine or cold shock is a widely used method to produce a fertile species hybrid, also known as an amphidiploid. This process usually results in a hybrid with double the number of chromosomes compared to the parent species, which can give it various desirable traits such as higher vigor, resistance to diseases or pests, and increased yield.

Doubling the Chromosomes of a Sterile Species Hybrid with Colchicine