What two terms apply to the fusion of cultured human and mouse cells that produces cell lines that are useful in assigning a gene to a particular human chromosome?
A) forward and reverse
B) lod score and pod score
C) heterokaryon and synkaryon
D) single and double
E) positive and negative

Question

Quizplus · Accepted Answer

Heterokaryon refers to a cell that contains two or more nuclei from different cells, while synkaryon refers to a cell that has undergone fusion to form a single nucleus. By fusing human and mouse cells, a heterokaryon or synkaryon can be produced, which allows the identification of genes on human chromosomes based on their expression in mouse-human hybrid cell lines. Therefore, the terms heterokaryon and synkaryon apply to the fusion of cultured human and mouse cells that produces cell lines useful in assigning a gene to a particular human chromosome.

What Two Terms Apply to the Fusion of Cultured Human