The following laboratory results have been obtained for a 40-year-old woman with infrequent bleeding: PT = 20 seconds (reference range is 11 to 15 seconds), APTT = 50 seconds (reference range is 22 to 40 seconds).What factor deficiency is most likely?

Question

Quizplus · Accepted Answer

The prolonged PT and APTT suggest a deficiency in a factor common to both the intrinsic and extrinsic pathways, which points to Factor X deficiency. Factor VII deficiency would primarily prolong PT, while Factor VIII and XIII deficiencies would primarily affect APTT. Factor X is involved in both pathways, making it the most likely deficiency given the lab results.

The Following Laboratory Results Have Been Obtained for a 40-Year-Old