What is the isoelectric point of glutamic acid (pK_a of α-CO₂H, 2.10; pK_a of β-CO₂H, 4.07; pH of α-NH₂, 9.47)?

Name: What is the isoelectric point of glutamic acid (pK a of α-CO 2 H, 2.10; pK a of β-CO 2 H, 4.07; pH of α-NH 2 , 9.47)?
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Quizplus · Accepted Answer

The isoelectric point (pI) is calculated by averaging the pKa values of the acidic groups that lose protons around the neutral form. For glutamic acid, this is the average of the pKa values of the α-CO2H and β-CO2H groups: (2.10 + 4.07) / 2 = 3.08.

What Is the Isoelectric Point of Glutamic Acid (PKa of α-CO2H

What Is the Isoelectric Point of Glutamic Acid (PK_a of α-CO₂H