Which of the following sets of substituents are all meta directing in electrophilic aromatic substitution reactions? A) CN, NO_2, COCH₃ B) CH₃, OCH₃, COCH₃ C) Cl, NH₂, CH₃ D) CH₃, NH₃, OCH₃

Question

Quizplus · Accepted Answer

Meta-directing groups are typically electron-withdrawing groups through resonance or inductive effects. The groups listed in option A (CN, NO2, COCH3) are all known to be electron-withdrawing and thus direct electrophilic substitution to the meta position relative to where they are attached on the benzene ring.

Which of the Following Sets of Substituents Are All Meta