For Diels-Alder cycloaddition reactions to take place most rapidly and in highest yield a dienophile must be substituted with electron-donating groups.

Question

Quizplus · Accepted Answer

Diels-Alder reactions proceed most rapidly and in highest yield when the dienophile is substituted with electron-withdrawing groups, which make it more electrophilic and thus more reactive towards the electron-rich diene.

For Diels-Alder Cycloaddition Reactions to Take Place Most Rapidly and in Highest