Carboxylate anions are inert to nucleophilic acyl substitution because --_____.
A) carboxylate anions are negatively charged and therefore repel nucleophiles
B) carboxylate anions are resonance stabilized and therefore become neutral
C) carboxylate ions are positively charged and therefore repel nucleophiles
D) carboxylate anions are negatively charged and therefore attract nucleophiles

Question

Quizplus · Accepted Answer

Carboxylate anions are negatively charged, which leads to repulsion of nucleophiles, making them inert to nucleophilic acyl substitution reactions.

Carboxylate Anions Are Inert to Nucleophilic Acyl Substitution Because --_____