Which of the following most favors elimination rather substitution in a reaction with sodium methoxide?
A) bromomethane
B) bromoethane
C) 1-bromopropane
D) 2-bromopropane

Question

Quizplus · Accepted Answer

2-bromopropane is more likely to undergo elimination with sodium methoxide because it can form a more stable alkene (propene) through an E2 mechanism, favored by the bulky base (sodium methoxide) and the secondary carbon position of the halide.

Which of the Following Most Favors Elimination Rather Substitution in a Reaction