A 23-year-old male patient with hemophilia A says,"How can I keep my children from having hemophilia A?" Which of the following is the most informative response?

Question

Quizplus · Accepted Answer

Hemophilia A is an X-linked recessive disorder. Males are affected when they inherit the affected X chromosome from their carrier mother. A male with hemophilia A cannot pass the disorder directly to his sons, as males contribute a Y chromosome to their sons. However, his daughters will all be carriers because they will inherit his affected X chromosome. These daughters can then pass the affected gene to their children, putting her sons at risk of hemophilia A.

A 23-Year-Old Male Patient with Hemophilia a Says,"How Can I