How Is Rheumatoid Arthritis Distinguished from Osteoarthritis

How is rheumatoid arthritis distinguished from osteoarthritis?

A) Rheumatoid arthritis is an autoimmune,systemic disease;osteoarthritis is a degenerative disease of the joints.
B) Rheumatoid arthritis is an autoimmune,degenerative disease;osteoarthritis is a systemic inflammatory disease.
C) People with osteoarthritis are considered to be genetically predisposed;there is no known genetic component to rheumatoid arthritis.
D) Osteoarthritis is often caused by a virus;viruses play no part in the pathogenesis of rheumatoid arthritis.