What effect would cyanide poisoning and hypothermia have on VO₂ and the O₂ER?

Question

Quizplus · Accepted Answer

Cyanide poisoning inhibits cytochrome oxidase, the terminal enzyme in the electron transport chain, which leads to a decrease in oxidative phosphorylation and ATP production. This decrease in ATP production would lead to a decrease in VO₂. Hypothermia also decreases VO₂ by decreasing the metabolic rate. The O₂ER is the ratio of VO₂ to CO₂ production. Since both VO₂ and CO₂ production would decrease with cyanide poisoning and hypothermia, the O₂ER would not change.

What Effect Would Cyanide Poisoning and Hypothermia Have on VO2

What Effect Would Cyanide Poisoning and Hypothermia Have on VO₂