Why was Harriet Beecher Stowe's Uncle Tom's Cabin significant?

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Uncle Tom's Cabin, published in 1852, played a significant role in changing public opinion in the North towards slavery. It vividly depicted the harsh realities of slavery and humanized the slaves, thereby arousing sympathy and support for abolitionist causes. It did not start the American Renaissance, was not written by a former slave, nor was it the first commercially published book by an American woman.

Why Was Harriet Beecher Stowe's Uncle Tom's Cabin Significant