The spread of deadly diseases between Europe and the Americas followed which pattern?

Name: The spread of deadly diseases between Europe and the Americas followed which pattern?
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The spread of deadly diseases, such as smallpox, followed the pattern of Spain to the Caribbean to Mexico to the Andes, largely due to the Spanish conquest and colonization routes. Diseases were first introduced to the Caribbean islands by the Spanish, then spread to the mainland, affecting the Aztec and Inca empires.

The Spread of Deadly Diseases Between Europe and the Americas