The case of railroad worker Phineas Gage illustrates that

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The case of Phineas Gage is a famous example in the study of neuroscience and psychology because it demonstrated that injuries to the brain can significantly affect personality and behavior. Gage survived an accident in which a large iron rod was driven completely through his head, damaging much of his frontal lobe. This injury led to profound changes in his personality and behavior, providing early evidence that specific areas of the brain are involved in different aspects of personality and behavior.

The Case of Railroad Worker Phineas Gage Illustrates That