The last Ptolemaic ruler of Egypt prior to Egypt's entanglement with Rome was

Name: The last Ptolemaic ruler of Egypt prior to Egypt's entanglement with Rome was
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Cleopatra VII was the last Ptolemaic ruler of Egypt before her defeat by Rome in 30 BC. Ptolemy Soter was the founder of the Ptolemaic dynasty, Seleucus was a rival of the Ptolemies who founded the Seleucid Empire, and Antigonus was a general who fought in the wars of the Diadochi but never ruled over Egypt.

The Last Ptolemaic Ruler of Egypt Prior to Egypt's Entanglement