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Human Herpesvirus 8 Produces a Viral Homologue of the V-IRF α\alpha

Question 12

Multiple Choice

Human herpesvirus 8 produces a viral homologue of the v-IRF protein.Which of the following describes how this viral homologue inhibits the interferon pathway?


A) It binds to the interferon promoter and inhibits transcription.
B) It stimulates the expression of the Mx protein.
C) It blocks the activation of the PKR enzymes by double-stranded RNA.
D) It prevents binding of interferon α\alpha to its receptor.
E) It inactivates the caspase enzymes.

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