The Vpr from HIV can cause the infected cell to stall in the G2 stage of the cell cycle.What purpose does this serve for the virus?

Question

Quizplus · Accepted Answer

The G2 stage of the cell cycle is when transcription levels from the LTR (long terminal repeat) are the highest. The virus utilizes this stage to help promote its own replication and proliferation. By inducing the cell to remain in the G2 stage for an extended period of time, the virus can maximize its use of the host's cellular machinery for transcription and translation of viral genes, leading to greater viral replication and spread.

The Vpr from HIV Can Cause the Infected Cell to Stall