Treatment of cells infected with baculovirus with $\alpha$-amanitin toxin will inhibit immediate-early or early but not late viral gene expression.

Question

Quizplus · Accepted Answer

10-amanitin is a potent inhibitor of RNA polymerase II, which is responsible for transcribing immediate-early and early genes, but late viral gene expression in baculovirus is often driven by different mechanisms that are less sensitive to this toxin.

Treatment of Cells Infected with Baculovirus With α\alphaα -Amanitin Toxin Will Inhibit Immediate-Early or Early but Not Late

Treatment of Cells Infected with Baculovirus With $\alpha$ -Amanitin Toxin Will Inhibit Immediate-Early or Early but Not Late