Papillomaviruses Replicate in Differentiated Keratinocytes, Which Are Not Actively Dividing

Papillomaviruses replicate in differentiated keratinocytes, which are not actively dividing.How does the virus handle this situation?

A) They encode their own DNA replication enzymes.
B) Plasmid replication in the basal cells produces enough copies of the viral genome.
C) The viral E2 protein directly activates transcription of DNA replication genes.
D) The viral E6 protein binds to the p53 protein, causing it to be degraded.
E) The viral E7 protein binds to the pRb protein, forcing the cell into S phase.