Orofacial clefts are one of the most common craniofacial congenital defects.The presence of an orofacial cleft most likely indicates the presence of a syndrome.

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Orofacial clefts are indeed among the most common craniofacial congenital defects. However, the presence of an orofacial cleft does not most likely indicate the presence of a syndrome; most orofacial clefts occur as isolated defects without being part of a syndrome.

Orofacial Clefts Are One of the Most Common Craniofacial Congenital