Which of the Following Is NOT an Example of the Significance

Which of the following is NOT an example of the significance of Eli Whitney's cotton gin?

A) Cotton production increased dramatically in about a quarter of a century.
B) The Atlantic slave trade to the United States expanded in its last few years of existence.
C) The federal government moved to consolidate American control of the Deep South by driving out Native Americans and acquiring Florida.
D) The domestic slave trade grew.
E) The completion of the Erie Canal allowed the transportation of thousands of pounds of cotton per day.