In creating your female patient's pedigree, you note that she and both of her sisters were affected by the same genetic disorder. Although neither of her parents had indications of the disorder, her paternal grandmother and her paternal grandmother's two sisters were affected by the same condition. This pattern suggests:

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This pattern suggests an X-linked dominant disorder because the disorder is seen in females across generations, and males are not mentioned as being affected. The inheritance pattern skips generations and affects females, which is consistent with X-linked dominant inheritance, where a female with one affected X chromosome can display the disorder.

In Creating Your Female Patient's Pedigree, You Note That She