Which statement is TRUE?
A) In adulthood, nearly all individuals with Down syndrome develop amyloid plaques and neurofibrillary tangles.
B) In adulthood, nearly all individuals with Down syndrome develop cognitive impairments similar to those seen in patients with Alzheimer's disease.
C) The APOE gene has been implicated in both Down syndrome and Alzheimer's disease.
D) The PS1 gene has been implicated in both Down syndrome and Alzheimer's disease.

Question

Quizplus · Accepted Answer

Individuals with Down syndrome have an increased risk of developing Alzheimer's disease-like pathology, including amyloid plaques and neurofibrillary tangles, due to the extra copy of chromosome 21, which carries the APP gene associated with amyloid production.

Which Statement Is TRUE