Lidocaine is an amine used as a local anesthetic and cardiac depressant. When Lidocaine is administered,it is administered as its amine salt. Why is the amine salt,rather than the free amine,used?

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Quizplus · Accepted Answer

The amine salt form of lidocaine has a higher solubility in water and bodily fluids, which is crucial for its effectiveness and distribution when used as a local anesthetic or cardiac depressant. This increased solubility ensures that the drug can be easily administered and absorbed where needed.

Lidocaine Is an Amine Used as a Local Anesthetic and Cardiac