Which part of the DNA strand is the MOST polar, and what is the significance of that polarity?
A) The nitrogen base is most polar, and so it is on the outside of the DNA, in contact with water.
B) The nitrogen base is most polar, and so it is on the inside of the DNA.
C) The sugar phosphate backbone is most polar, and so it is on the outside of the DNA, in contact with water.
D) The sugar phosphate backbone is most polar, and so it is on the inside of the DNA.
E) No part of DNA is any more polar than any other part.

Question

Quizplus · Accepted Answer

The sugar phosphate backbone is the most polar part of the DNA strand, which makes it hydrophilic. This polarity allows the backbone to interact with the aqueous environment inside cells, while the less polar nitrogenous bases are stacked inside, away from water, stabilizing the DNA structure through hydrophobic interactions and hydrogen bonding between complementary bases.

Which Part of the DNA Strand Is the MOST Polar